Shanghai Brightol International Co., Ltd.  

Product Name: Hyaluronic Acid CAS Number 9004-61-9 Model NO.: Cosmetic and food grade Appearance: Powder Function: Skin Care Classification: Moisture Color: White Certification: ISO Environmental Protection: Yes EINECS: 232-678-0 Formula: (C14h21no11)N CAS No.: 9004-61-9 MOQ: 1kg Trademark: Brightol Transport Package: 1kg/Aluminum Foil Bag Specification: Cosmetic grade and food grade Origin: China HS Code: 39139000 Product Description Hyaluronic AcidBasic Information:Product Name:Hyaluronic AcidSynonyms: HA,Hyaluronic Acid, Sodium hyaluronate HyaluronanAppearance:White powderCAS: 9004-61-9Brand:BrightolGrade: Cosmetic, food gradeFunction:Cosmetic ingredientsPurity: >99%MF:(C14H22NNaO11)nPacking:Aluminum foil bag/kgWhat is Hyaluronia Acid(HA)?Hyaluronan (also called hyaluronic acid or hyaluronate) is an anionic, nonsulfatedglycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.Hyaluronan is a polymer of disaccharides, themselves composed of D-glucuronic acid andD-N-acetylglucosamine, linked via alternating beta-1,4 and beta-1,3glycosidic bonds. It can be obtained by extracting from cockscomb or through microorganismfermentatio. Function:Hyaluronan through the oral administration after the digestion absorption, increases in vivohyaluronan synthesis the precursor, causes in the skin and other organization's hyaluronanresultant quantity increases, thusenables the skin the water retention property to increase,rich elasticity, wrinkle reduction.Medical applications:Hyaluronan could be used in eye surgery, such as corneal transplantation, cataract surgery,glaucoma surgery, and surgery to repair retinal detachment.Hyaluronan can also be used to treat osteoarthritis of the knee. They are administered as acourse of injections into the knee joint, which are believed to supplement the viscosity of thejoint fluid, thereby lubricating the joint, cushioning the joint, and producing an analgesic effect.Hyaluronan has also been used in the synthesis of biological scaffolds for wound-healingapplications. These scaffolds typically have proteins such as fibronectin attached to thehyaluronan to facilitate cell migration into the wound.Hyaluronan is also used in anti-adhesive products, which are widely used in pelvic andabdominal surgery to prevent postoperative adhesions.Cosmetics applications:Hyaluronan has outstanding moisture keeping ability, thus called Natural Moisturing Factor in theworld. Hyaluronan is a common ingredient in skin-care products, which can be used as a veryeffective topical humectant.In 2003, the FDA approved hyaluronan injections for filling soft tissuedefects, which can be used for facialTDS:ITEMSPECIFICATIONAppearance:White or almost white powderSodium Hyaluronate(dry basis):90.0% Min.Glucuronic Acid:42.0% Min.PH(0.1% Solution):6.0~7.5Molecular Weight:0.8 Million Da Min. Protein:0.1% Max.Transparecy(0.1% Solution):99.0% Min.Loss on Drying:10.0% Max.Heavy metal(As Pb):20 ppm Max.Arsenic:2 ppm Max.Bacteria Count:100 cfu/g Max.Mold&Yeast:10 cfu/g Max.Salmonella:NegativeColiforma:NegativePseudomonas aeruginosa:NegativeStaphylococcus aureus:Negative